N-Glycosylation effects on T cell receptor kinetics
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下载链接：
http://datadryad.org/dataset/doi%253A10.25338%252FB8Q05W
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资源简介：
This methodology is an atomic-level investigation of the physiochemical effects of glycosylation on TCR dissociation kinetics. The force-dependent bond lifetime and bond strength of the DMF5 T Cell Receptor (TCR) to the MART1 peptide-Major Histocompatibility Complexes (pMHCs) were simulated using Steered Molecular Dynamics. N-glycsoylated and aglycosylated configurations were compared in triplicate. This data set contains atomic structure of the TCR and pMHC (.gro files), atomic interactions between the TCR and pMHC (hmap & cmap .csv files), and rendered trajecories of the pulling simulations (.mp4).
Methods
Data was collected and processed on high performance computers (hpc1/hpc2) at the University of California, Davis College of Engineering.
创建时间：
2021-12-03
