The effect of CDK6 expression on DNA methylation and DNMT3B regulation. The effect of CDK6 expression on DNA methylation and DNMT3B regulation
收藏NIAID Data Ecosystem2026-03-11 收录
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资源简介：
We performed methylation analyses in BCR-ABL+ cells either expressing or lacking CDK6 using the next-generation sequencing approach RRBS and identified DNA methylation changes towards both hyper- and hypomethylation. CDK6 mediated methylation changes are largely reverted by CDK6 re-expression in this experimental system. Overall design: 3 BCR-ABL+/CDK6wt cell lines, 3 BCR-ABL+/CDK6-/- cell lines, 3 BCR-ABL+/CDK6-/-+Cdk6 cell lines.
创建时间：
2020-02-12
