Deconstructing stem cell populations in intestinal adenoma by single-cell RNA-seq
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介：
The identity of tumor stem cell populations in intestinal adenoma remains uncharacterized definitively. Here we performed single-cell transcriptomic profiles of Lgr5-GFPhigh, p57-tdTomato+ and whole cell populations in the adenoma, and revealed that a spatiotemporal reprogramming event resembling post-injury regeneration of normal crypts is associated to the facultative acquisition of stemness in intestinal adenoma cell populations.
创建时间：
2022-04-24
