Heavy Metal Impact on Rat Respiratory Microbiota and Lung Health

This study investigates the combined effects of nickel (Ni), copper (Cu), and arsenic (As) on the bronchoalveolar lavage fluid (BALF) microbiota in rats, and explores their potential role in lung injury. The research found dose-dependent structural lung damage and significant declines in lung function, along with significant disruptions in the lower respiratory microbiota. The study highlights the critical link between environmental metal exposure and respiratory health, advocating for tighter control of metal pollutants.