Overlapping representations of food and social stimuli in VTA dopamine neurons
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下载链接:
http://datadryad.org/dataset/doi%253A10.5061%252Fdryad.7sqv9s4xs
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资源简介:
2-photon imaging and behavioral data accompanying publication of "Overlapping representations of food and social stimuli in VTA dopamine neurons" (Lindsay Willmore, Adelaide Minerva, Ben Engelhard, Brenna McMannon, Nirja Oak, Stephan Thiberge, Malavika Murugan, Catherine Jensen Pena, Ilana Witten). This dataset contains all information required to recreate figures from the paper.
Methods
Transgenic mice expressing the calcium-sensitive fluorescent indicator GCamp6f in dopamine neurons were used to perform 2-photon calcium imaging of ventral tegmental area as mice were presented with various social and food stimuli. See paper for detailed paradigm methods. Regions of interest (ROIs) containing putative single neurons were extracted using suite2p.
Contents of this dataset include:
2p_aligned: aligned time traces for imaging ROIs & neuropil; syncing signals for behavior analysis
2p_ops: output ROIs and statistics from suite2p for each imaging session
body: DeepLabCut tracking files for points on the body of the imaged and stimulus mice for each relevant imaging session
pupil: DeepLabCut tracking files for points on the pupil of the imaged mouse for each relevant imaging session
tongue: tracking of if the tongue was seen as a proxy for licking for each relevant imaging session
usv: syllable_sequence files from MUPET across sessions, usv_count summary syllable count data across sessions, example raw data from a single session
Analysis code: https://github.com/lwillmore/SocialVTA2p
创建时间:
2023-06-30



