Genome-wide epigenetic cross-talk between DNA methylation and H3K27me3 in zebrafish embryos. Danio rerio

DNA methylation and histone modifications are epigenetic marks implicated in the complex regulation of vertebrate embryogenesis. The cross-talk between DNA methylation and Polycomb-dependent H3K27me3 histone mark has been reported in a number of organisms and both marks are known to be required for proper developmental progression. Here we provide genome-wide DNA methylation (MethylCap-seq) and H3K27me3 (ChIP-seq) maps for three stages (dome, 24hpf and 48hpf) of zebrafish (Danio rerio) embryogenesis, as well as all analytical and methodological details associated with the generation of this dataset. Overall design: DNA methylation (MethylCap-seq) and H3K27me3 (ChIP-seq) profling of zebrafish embryogenesis