Genotypic distribution of CD associated genetic variants.

Four SNPs on three genes (NOD2, IL23R and 3p21 region) were significantly associated with paediatric onset Crohn's disease (CD) (p<0.05). Main NOD2 variants = SNP rs2066845, SNP rs2066844, rs5743293. Three SNPs on two paediatric specific CD susceptibility genes (PSMG1 and TNFRSF6B) showed a trend of association (p<0.1), X2 = Pearson Chi Square analysis, F = Fisher's exact test analysis, OR = odds ratio, CI = confidence interval.