Crystal structure of the human PAD2 protein bound to small molecule

Crystal structure of the human PAD2 protein bound to small molecule Descriptor: (5P)-N,N-diethyl-2-fluoro-5-(2-[({1-[2-(methylamino)-2-oxoethyl]cyclohexyl}methyl)amino]-6-{methyl[1-(2-methyl-1-phenyl-1H-1,3-benzimidazole-5-carbonyl)piperidin-4-yl]amino}pyrimidin-4-yl)benzamide, ACETATE ION, CALCIUM ION, ... Authors: Byrnes, L.J, Vajdos, F. Deposit date: 2024-04-01 Release date: 2024-10-09 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.003 Å) Cite: Discovery, Characterization, and Structure of a Cell Active PAD2 Inhibitor Acting through a Novel Allosteric Mechanism. Acs Chem.Biol., 19, 2024