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Crystal structure of Aminopeptidase N in complex with the phosphinic dipeptide analogue LL-(R,S)-2-(pyridin-3-yl)ethylGlyP[CH2]Phe

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of Aminopeptidase N in complex with the phosphinic dipeptide analogue LL-(R,S)-2-(pyridin-3-yl)ethylGlyP[CH2]Phe Descriptor: 3-{[(R)-1-amino-3-(pyridin-3-yl)propyl](hydroxy)phosphoryl}-(S)-2-benzylpropanoic acid, Aminopeptidase N, GLYCEROL, ... Authors: Nocek, B, Joachimiak, A, Berlicki, L, Vassiliou, S, Mucha, A. Deposit date: 2014-06-01 Release date: 2014-09-24 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.701 Å) Cite: Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J.Med.Chem., 57, 2014
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2014-06-01
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