International Collaboration of Incident HIV and HCV in Injecting Cohorts (InC3)

23203695). Of the 10 cohorts, six provided data and samples for the genome wide association study (GWAS) entitled “Genetic Analysis of Opioid Addiction in People Who Inject Drugs”. The InC3 cohorts included in the GWAS were: i) Australian Trial in Acute Hepatitis C (ATAHC-I, Sydney); ii) Hepatitis C Incidence and Transmission Study in Prison (HITS-p) (Sydney); iii) Hepatitis C Incidence and Transmission Study in Community (HITS-c) (Sydney); iv) HepCo Study (Montreal); v) SuperMIX Study (combining the Networks II & MIX studies, Melbourne); and vi) the UFO Study (San Francisco).]]>
Various, but generally: people who inject drugs (PWID) who were uninfected with hepatitis C at enrollment and were followed prospectively for incident hepatitis C infection.]]>
The established InC3 merged behavioral databases and stored specimens and provided an opportunity to support the investigation of genetic variants for opioid dependence. ]]>