Systematic Study on the Three-Dimensional Genome of Escherichia Coli and Its Thermal Adaptation Mechanism (3C-Seq)

Chromosome conformation capture and sequencing experiments were carried out at 37? and 45? for E. coli in logarithmic phase and stable phase, respectively. Three-dimensional DNA interaction data of E. coli under four different growth conditions and control group were obtained Overall design: The 3D genomic data of Escherichia coli cultured at 45? and 37? to log phase and stable phase were extracted and cross-compared