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Helically Chiral 1‑Sulfur-Functionalized [6]Helicene: Synthesis, Optical Resolution, and Functionalization

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The synthesis and optical resolution of helically chiral 5,6,9,10-tetrahydro-1-[6]­helicenethiol and its subsequent transformations to enantiopure 1-sulfur-functionalized [6]­helicenes are reported. A novel enantiopure [7]­thiahelicene having a thiophene ring at the terminal position of the [6]­helicene skeleton was synthesized.

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2017-06-07
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