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Directly converted astrocytes retain the ageing features of the donor fibroblasts and elucidate the astrocytic contribution to human CNS health and disease.

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DataCite Commons2021-01-25 更新2025-04-16 收录
下载链接:
https://figshare.shef.ac.uk/articles/dataset/Directly_converted_astrocytes_retain_the_ageing_features_of_the_donor_fibroblasts_and_elucidate_the_astrocytic_contribution_to_human_CNS_health_and_disease_/12162282
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资源简介:
To interrogate the transcriptional features of fibroblast-derived iAstrocytes in relation to their ageing phenotype, we compared transcriptomic data from iAstrocytes obtained from old and young donors to bona fide aged human astrocytes laser captured from post-mortem (PM) brains and fetal primary astrocytes.Research Ethics:Study number STH16573, Research Committee reference 12/YH/0330 and MODEL-AD research study number STH19080 Research and Ethics Committee number: 16/YH/0155<br>
提供机构:
The University of Sheffield
创建时间:
2020-04-22
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