Menin bound to M-1121
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Menin bound to M-1121 Descriptor: Menin, methyl {(1S,2R)-2-[(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-{1-[(3-methoxy-1-{4-[(1S,4S)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptane-2-sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}ethyl]cyclopentyl}carbamate, praseodymium triacetate Authors: Stuckey, J. Deposit date: 2021-03-22 Release date: 2021-08-11 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.74 Å) Cite: Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression. J.Med.Chem., 64, 2021
创建时间：
2021-03-22
