Peripheral blood CD4+ T cells in HIV-1+ patients are coated with Ig. However, the causes and consequences of the presence of Ig+ CD4+ T cells remain unknown. Previous studies have demonstrated the rap

NIAID Data Ecosystem60

Circulating Monocytes in HIV-1 infected Viremic Subjects Exhibit an Anti-Apoptotic Gene Signature

HIV-1免疫

细胞抗凋亡机制

Mechanisms that may allow circulating monocytes to persist as CD4 T cells diminish in HIV-1 infection have not been investigated. We have characterized steady-state gene expression signatures in circu

NIAID Data Ecosystem40

Additional file 8 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

单细胞转录组学

HIV-1免疫

Additional file 8. Table S11: Genes differentially expressed between HIV-1-treated compared to seronegative CD4+ T cells.

Figshare2022-09-30 更新60

Data_Sheet_1_Altered Expression of CD300a Inhibitory Receptor on CD4+ T Cells From Human Immunodeficiency Virus-1-Infected Patients: Association With Disease Progression Markers.PDF

HIV-1免疫

疾病进展分子标志物

The ability of the CD300a inhibitory receptor to modulate immune cell functions and its involvement in the pathogenesis of many diseases has aroused a great interest in this molecule. Within human CD4

NIAID Data Ecosystem50

Crystal structure of MHC CLass I HLA-A2.1 bound to HIV-1 envelope peptide env120-128

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