Genomic arrangement of the synthetase and glutaminase components in NAD synthetase and other families of ATP-dependent amidotransferases.

1Gene names are as in E. coli except gatABC and yaaDE that are as in B. subtilis (not present in E. coli). 2 A current classification of glutaminase domains (subunits) of amidotransferases includes four classes of nonhomologous enzymes: Class I (contains a catalytic triad in the active site); Class II (contains a catalytic Cys at the N-terminus); Class III (a relatively poorly explored glutaminase subunit of GatABC complex); and Class IV (nitrilase-like glutaminase component of NADS). 3 Percentage (%) of total number of arrangements within analyzed genomes.