Nature and distribution of PAX-FOXO1 related motifs in PAX-FOXO1s bound cis-regulatory modules (CRMs).

Sheet 1: PWM for 21 DNA binding motifs previously identified for PAX3, PAX7 and PAX3-FOXO1 as well as bHLH and FOXO1. Sheet 2: Distribution of all 21 PWM across cluster 1, 2 and 3 defined in Fig 1B. The adjusted p-value was calculated by AME of the MEME-suite and correspond to “The optimal enrichment p-value of the motif according to the statistical test, adjusted for multiple tests using a Bonferroni correction. If the best p-value is p before adjustment, and the number of multiple tests is n, then the adjusted p-value is 1 - (1-p)n”. (XLSX)