MeDIP-seq profiles of mouse ApcDHep hepatocytes at day 6 vs wt hepatocytes
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We analyzed the level of DNA methylation by MeDIPseq in hepatocytes isolated by collagenase perfusion from Apclox/loxlivers, six days after injection of 2mg tamoxifen vs wt hepatocytes. Our aims was to study the impact of the beta-catenin on DNA methylation during the early steps of liver tumorigenesis Overall design: DNA isolated from mouse ApcDHep hepatocytes at day 6 vs wt hepatocytes by Phenol/chloroform technique was immunoprecipitated by anti-5-methylcytosine (Active motif)
创建时间：
2024-04-01
