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Crystal structure of the kinase domain of human PAK1 in complex with compound 15

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of the kinase domain of human PAK1 in complex with compound 15 Descriptor: Serine/threonine-protein kinase PAK 1, [2-chloro-5-(hydroxymethyl)phenyl]{5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridin-3-yl}methanone Authors: Ferguson, A.D. Deposit date: 2014-04-01 Release date: 2014-09-10 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Identification and optimisation of 7-azaindole PAK1 inhibitors with improved potency and kinase selectivity. MEDCHEMCOMM, 2014
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2014-04-01
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