X-ray crystal structure of SARS-CoV-2 main protease quadruple mutants in complex with Nirmatrelvir
收藏Protein Data Bank Japan2026-01-21 更新2026-04-04 收录
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X-ray crystal structure of SARS-CoV-2 main protease quadruple mutants in complex with Nirmatrelvir Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 1,2-ETHANEDIOL, 3C-like proteinase nsp5, ... Authors: Esler, M.A, Shi, K, Harris, R.S, Aihara, H. Deposit date: 2024-07-07 Release date: 2025-07-09 Last modified: 2026-01-21 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Structural basis for varying drug resistance of SARS-CoV-2 M pro E166 variants. Mbio, 16, 2025
创建时间：
2024-07-07
