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Serine/threonine-protein kinase PAK1 complexed with a dibenzodiazepine: identification of an allosteric site on PAK1

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Serine/threonine-protein kinase PAK1 complexed with a dibenzodiazepine: identification of an allosteric site on PAK1 Descriptor: 2,8-difluoro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, GLYCEROL, Serine/threonine-protein kinase PAK 1 Authors: Bellamacina, C.R, Bussiere, D.E. Deposit date: 2015-05-01 Release date: 2015-08-05 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. Acs Med.Chem.Lett., 6, 2015
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2015-05-01
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