FaceBase

FaceBase is a collaborative NIDCR-funded consortium to generate data in support of advancing research into craniofacial development and malformation. It serves as a community resource by generating large datasets of a variety of types and making them available to the wider research community via this website. Practices emphasize a comprehensive and multidisciplinary approach to understanding the developmental processes that create the face. The data offered spotlights high-throughput genetic, molecular, biological, imaging and computational techniques. One of the missions of this consortium is to facilitate cooperation and collaboration between projects.FaceBase是由美国国家牙科与颅面研究所（National Institute of Dental and Craniofacial Research, NIDCR）资助的合作型科研联盟，旨在生成数据以支撑颅面发育与畸形领域的研究进展。该联盟通过构建多类型大型数据集，并依托本网站向全球科研社区开放共享，以此打造公共科研资源。其研究范式强调采用全面且多学科的研究路径，解析构建面部结构的发育机制。本次公开的数据重点展示了高通量遗传、分子、生物学、成像及计算技术的相关应用。该联盟的核心使命之一，是促进各参与项目间的合作与协同。

搜集汇总

背景与挑战

背景概述

FaceBase是一个由NIDCR资助的协作联盟，旨在为颅面发育和畸形研究提供高质量数据资源，作为一个统一平台整合多种数据类型（如遗传、成像和表型数据），遵循FAIR原则以促进开放共享和跨学科合作。它通过集中式存储库连接全球研究人员，支持模型生物和人类研究，加速科学发现和临床成果。