Knowledge network of the protective molecules against Pneumolysin

PLY interactions (edges) with host molecules (cyan circles), cells (cyan rectangles), and cellular processes (orange diamonds) is shown. Three types of connections are distinguished: the red arrows indicate inhibition (?) whereas the blue arrows refer to activation (?) and the grey arrows show interactions without inhibition or activation. The width of the lines reflects article ranking. The right panel represents the abundance and color of the molecules grouped by type. The network was built using Cytoscape software after text mining articles with EXTRACT 2.0.