High-confident T2D candidate genes and their homozygous SNVs in GK rat.

a. Additional evidence of association with T2D. 1) T2D prior genes curated from literatures. 2) Protein-protein interaction partners are enriched with T2D prior genes. 3) Differential expression or differential co-expression in GSE13271 dataset.b. P-value for enrichment of T2D prior genes in the interaction partners. P-value was calculated by fisher test, and was adjusted by p.adjust in R.c. Differential expression between GK and Wistar rats.d. Differential co-expression between GK and Wistar rats.High-confident T2D candidate genes and their homozygous SNVs in GK rat.