Single cell RNA sequencing for CD34 lineage cells from normal and Angiotensin ?-induced abdominal aneurysmal aorta

The development of aneurysm is involved in imbalance between connective tissue repair and degradation. CD34+ cells are a heterogeneous population with stem/progenitor cell properties. However, the role of CD34+ cells in abdominal aortic aneurysms/dissections (AAAs) is unknown. We aimed to uncover the exact role and potential mechanism of CD34+ cells in the development of AAAs. Overall design: This entry contains 10x Single-cell RNA-seq data of FACS sorted nucleated living tdTomato+ cells from normal or tdTomato+CD45- cells from 4-week Angiotensin ?-induced mouse abdominal aorta.