Dietary Differences Mediate Gut Microbiota Remodeling, Metabolite Alterations, and Host-Microbial Interactions in Mandarin Fish (Siniperca chuatsi)

Dietary regimen exerts a dominant influence in reshaping the gut microbiota structure and microbial metabolite types and levels in S. chuatsi, subsequently affecting host physiological functions like immunity, and has a more pronounced effect than environmental factors. These findings offer new insights into the dietary-microbiota-host interaction network, and fill the gap in the understanding of the significant role that diet plays in contributing to the gut microbiota.