Gasdermin D Mediates Endoplasmic Reticulum Stress via FAM134B to Regulate Cardiomyocyte Autophagy and Apoptosis in Doxorubicin-induced Cardiotoxicity
收藏NIAID Data Ecosystem2026-05-01 收录
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These results suggest that GSDMD promotes autophagy and induces cardiomyocyte apoptosis by modulating the reaction of FAM134B and LC3, thereby promoting DIC injury. Targeted regulation of GSDMD may be a new target for the prevention and treatment of DIC. Overall design: We used GSDMD knockout mice and control mice for DOX treatment.
创建时间：
2023-10-01
