Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545
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Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545 Descriptor: 4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE, POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 Authors: Kato, M, Li, J, Chuang, J.L, Chuang, D.T. Deposit date: 2007-06-10 Release date: 2007-07-24 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure, 15, 2007
创建时间：
2007-06-10
