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Oxidative Nucleophilic Cyclization of 2‑Alkynylanilines with Thiophenols under Metal-Free Conditions

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Figshare2016-02-16 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Oxidative_Nucleophilic_Cyclization_of_2_Alkynylanilines_with_Thiophenols_under_Metal_Free_Conditions/2224018
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An oxidative nucleophilic cyclization of 2-alkynylanilines with thiophenols under metal-free conditions was developed. The one-pot two-step reaction involves a PhI­(OAc)2-mediated oxidative dearomatization and a Brønsted acid promoted nucleophilic cyclization. DFT calculations were performed to understand the reaction pathway.
创建时间:
2016-02-16
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