IL-2-dependent gene expression by human regulatory T cells
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IL-2-dependent gene expression by human regulatory T cells
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2015-07-09
相关数据集
Dendritic cell-derived IL-2 promotes apoptosis of terminally mature cells via a novel autocrine signaling pathway
Dendritic cells (DCs) are crucial for sensing pathogens and triggering immune response. GM-CSF myeloid dendritic cells (GM-DCs) secrete several cytokines including IL-2 upon activation by pathogen ass
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Investigating the role of IL-2 in shaping the epigenome in T cells [RNA-seq]
During T cell activation hundreds of genes are primed for efficient activation. Here we show that IL-2 signaling is required to maintain open chromatin at gene regulatory elements which are associated
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IL2 signaling events mediated by PI3K (v2.0)
This is the updated version of an original NCI Pathway Interaction Database (PID) network. The list of entities (genes, proteins, chemicals, etc) from the original network was used to query the INDRA
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Full-length transcriptome sequencing of lymphocytes after stimulation with IL-2 in flounder
In this study, full-length transcriptome sequencing was performed to investigate the activation of IL-2 on flounder lymphocytes in vitro, the related immune pathways in lymphocytes after IL-2 stimualt
NIAID Data Ecosystem70
A function for interleukin 2 in Foxp3-expressing regulatory T cells. Mus musculus
Regulatory T cells (Treg cells) expressing the forkhead family transcription factor Foxp3 are critical mediators of dominant immune tolerance to self. Most Treg cells constitutively express the high-a
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