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Crystal Structure of Human Myt1 Kinase domain Bounded with compound 39

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Protein Data Bank Japan2023-10-18 更新2026-05-23 收录
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Crystal Structure of Human Myt1 Kinase domain Bounded with compound 39 Descriptor: (1P)-2-amino-5-bromo-1-(3-hydroxy-2,6-dimethylphenyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide, 1,2-ETHANEDIOL, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, ... Authors: Pau, V.P.T, Mao, D.Y.L, Mader, P, Orlicky, S, Sicheri, F. Deposit date: 2022-06-06 Release date: 2022-07-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306. J.Med.Chem., 65, 2022

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2022-06-06
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