aTwo-sided χ2 test for the distributions of genotypes. bAdjusted for age, gender, BMI, smoking status, drinking status, hypertension and diabetes in logistic regression model.
Most clear cell renal carcinomas (ccRCCs) are initiated by somatic inactivation of the VHL tumor suppressor gene. The VHL gene prod- uct, pVHL, is the substrate recognition unit of an ubiquitin ligase
The aim of CAGEKID is to carry out comprehensive detection of DNA markers for conventional (clear cell) renal carcinoma. The project includes complete analysis of somatic and constitutional DNA variat