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RNA-Seq transcriptome profiling of estrogen-related receptor alpha and gamma (ERRa/g) knock out (KO) human iPS cell-derived cardiomyocytes (hiPSC-CMs)

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NIAID Data Ecosystem2026-03-13 收录
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Transcriptional regulatory circuits that drive cardiomyocyte maturation are poorly understood. Here we found that in ERRa/g KO hiPSC-CMs, cardiac energy metabolic and cardiac structural transcriptional programs are dysregulated. Examination of gene expression levels in wild type control or ERRa/g KO hiPSC-CMs from two different lines with CRISPR/Cas9

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2022-05-05
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