five

The zebrafish CreZoo

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国家生物信息中心2025-10-11 更新2025-03-15 收录
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http://crezoo.crt-dresden.de
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资源简介:
A new open access database containing novel CreER(T2)-driver lines that express Cre fused to the mutated human ligand-binding domain of the estrogen receptor (CreER(T2)) in several tissues of zebrafish. Currently the number of CreER(T2)-driver lines is limited. To enlarge the pool of existing CreER(T2)-driver lines, we conducted a genome-wide screen using a gene trap cassette comprising a splice acceptor and an mCherry-tagged variant of CreER(T2). All molecular and expression data obtained in this screen are summarized in the CreZoo database, which currently comprises an inventory of about 47 Cre-driver lines expressing CreER(T2) in a cell- and tissue-specific manner during development and adulthood.
提供机构:
Dresden University of Technology
创建时间:
2018-01-28
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