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Expedient Metal-Free Synthesis of 1,3-Oxazinen-4-ones

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https://figshare.com/articles/dataset/Expedient_Metal_Free_Synthesis_of_1_3_Oxazinen_4_ones/2215411
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资源简介:
1,3-Oxazinen-4-ones are medicinally important scaffolds which have traditionally been accessed using a hetero-Diels–Alder approach or more recently using a cobalt-catalyzed three-component cycloaddition. Herein we report a novel strategy to access this scaffold which allows for the rapid and high yielding synthesis of 1,3-oxazinen-4-ones under ambient temperature and pressures with improved substrate scope.
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2016-02-16
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