Cell-surface proteins on tumor cells serve as both key targets for immunotherapeutic strategies and markers of blast phenotype and differentiation status. Compounds that modulate surface expression of

NIAID Data Ecosystem40

Mean squared error (MSE) and earthmoving distance for VAE’s ability to reconstruct Cell Painting and L1000 profiles.

生物数据重构评估

药物高通量筛选

We compare these values with results derived from shuffled models. Earthmoving distance is calculated by taking the mean of the earthmoving distance of each sample. We add the 95% percentile range of

NIAID Data Ecosystem30

Bioactivity of pure compounds at different doses.

化合物效力评估

剂量反应关系

“P” indicates the statistical significance of the difference between treatment and negative control (n.s. = no statistically significant difference). “Treatment/negative control” represents the rati

NIAID Data Ecosystem70

Additional file 1 of High-throughput screening of clinically approved drugs that prime nonviral gene delivery to human Mesenchymal stem cells

药物高通量筛选

干细胞基因递送

Additional file 1: Supplemental Data. NCC Screen Fold Changes. Excel spreadsheet containing all fold changes for Hoechst-count, viability, transfection efficiency, EGFP cell-count, transgene productio

Figshare2020-05-20 更新40

Results for the top 50 hits from the screen at 100 μM for 24 hours.

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