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Crystal structure of the ATP-gated human P2X3 ion channel bound to competitive antagonist A-317491

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal structure of the ATP-gated human P2X3 ion channel bound to competitive antagonist A-317491 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-{[(3-phenoxyphenyl)methyl][(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}benzene-1,2,4-tricarboxylic acid, MAGNESIUM ION, ... Authors: Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E. Deposit date: 2016-08-07 Release date: 2016-10-05 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.13 Å) Cite: X-ray structures define human P2X3 receptor gating cycle and antagonist action. Nature, 538, 2016
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2016-08-07
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