Effects of Conditional Egfr deletion on transcriptome of the mouse cerebral cortex

To investigate the role of Egfr in the cerebreal cortex and hippocampal formation we conditionally deleted it using a floxed allele in combination with the Nestin-cre transgene. Cortices at E17.5 embryonic stage were harvested and split into rostral and caudal halves and RNA extracted and sequenced Comparison of RNA-seq data between rostral and caudal cortices and hippocampal formation of control brains (EgfrF/+ gentoype) and brain-specific knock of Egfr (Nestin-EgfrF/F).