HUMAN ERK2 WITH ERK1/2 INHIBITOR, AZD0364.
收藏Protein Data Bank Japan2024-05-15 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6slg
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HUMAN ERK2 WITH ERK1/2 INHIBITOR, AZD0364. Descriptor: (6~{R})-7-[[3,4-bis(fluoranyl)phenyl]methyl]-6-(methoxymethyl)-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5,6-dihydroimidazo[1,2-a]pyrazin-8-one, 1,2-ETHANEDIOL, ERK-tide, ... Authors: Breed, J, Phillips, C. Deposit date: 2019-08-19 Release date: 2019-11-20 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.33 Å) Cite: Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC). J.Med.Chem., 62, 2019
创建时间：
2019-08-19
