Enantioselective Bromocyclization of Tryptamines Induced by Chiral Co(III)-Complex-Templated Brønsted Acids under an Air Atmosphere
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https://figshare.com/articles/dataset/Enantioselective_Bromocyclization_of_Tryptamines_Induced_by_Chiral_Co_III_-Complex-Templated_Br_nsted_Acids_under_an_Air_Atmosphere/6387497
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资源简介:
The
chiral Co(III)-complex-templated Brønsted acids were found
to be efficient bifunctional phase-transfer catalysts for the highly
enantioselective bromocyclization of protected tryptamines with readily
available N-bromosuccinimide (NBS) under an air atmosphere.
The 3-bromohexahydropyrrolo[2,3-b]indoles, which
are key building blocks of cyclotryptamine alkaloids, were thus obtained
in up to 95% yield and 93.5:6.5 er.
创建时间:
2018-06-06



