“KMSKS-Motif 1” codon assignment.

First and last row are consensus residues according to the structure-based MSA, “+” indicates gaps. Signature regions according to [8] are emphasized. Sequence numbers are given according to the MSA. Middle rows indicate consensus codons; unassigned positions are indicated by dots, matches by vertical lines, and mismatches by “x”. The C-terminal Backbone Brackets residue is framed by a box. Sequence positions were omitted if both complementary sequences feature low occupancy, and are therefore not necessarily consecutive.