Clinical characteristics of the study groups.

No individual had diabetes. The lean children group is not included.Values are median (25th,75th percentile). SMC samples (81 lean females (BMI2) and 76 overweighed/mildly obese females (28≤BMI2)) had no data for these characteristics but are included in the total n. For SDPP, blood lipid data was available from 172 lean, 103 overweighed/mildly obese and 9 severely obese individuals. Other data was available from all SDPP individuals. The lean children group is not included here since these characteristics were unknown for them.aThose on pharmacological treatment for high blood lipid levels (statins or fibrates) were excluded.bHOMA-IR was not analyzed in children because limited correlation with Si in children [41].pFasting plasma levels. Otherwise, data are fasting serum levels.