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Tet-mediated DNA methylation dynamics affect chromosome organization. Mus musculus

NIAID Data Ecosystem2026-05-01 收录

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基因组三维结构

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1066533 数据链接链接失效反馈

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In this research, we performed Methyl-HiC experiment on Tet-triple knock out mESC to investigate how DNA methylation variation affected high-order genome architecture.

应用场景：

创建时间：

2024-01-19

毛囊上皮分化

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Execution of lineage-specific differentiation programs requires tight coordination between many regulators including Ten-eleven translocation (TET) family enzymes catalyzing 5-methylcytosine oxidation

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The abnormal tumor vasculature can present a barrier to the infiltration of anti-tumor immune cells, which impairs immune surveillance and response to immunotherapy. Here, we show that targeting the e

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Histone modifiers instruct cellular differentiation, yet how they achieve temporal precision remains enigmatic. Here we demonstrate that the H3K27 demethylase Kdm6b acts as a master epigenetic conduct

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Tet-mediated DNA methylation dynamics affect chromosome organization. Mus musculus

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