WP3646 - Hepatitis C and hepatocellular carcinoma - Homo sapiens
收藏NIAID Data Ecosystem2026-05-02 收录
下载链接：
https://www.ndexbio.org/viewer/networks/177b9122-5c6c-11ec-b3be-0ac135e8bacf
下载链接
链接失效反馈官方服务：
资源简介：
Pathway model based on hub miRNAs and their putative targets from network analysis.
* From a set of differentially expressed genes in both chronic HCV (hepatitis C virus) and HCC (hepatocellular carcinoma) samples, a protein-protein network was constructed using [STRING](http://string-db.org/) and [GeneMANIA](http://genemania.org/).
* After topological analysis and network visualization in Cytoscape, the top hub genes were identified.
* miRNAs related to hub genes were identified using miRTarBase server and combined with the PPI network to constructed a miRNA-Hubgene network.
Based on Figure 4 from Poortahmasebi et al, How Hepatitis C Virus Leads to Hepatocellular Carcinoma: A Network-Based Study.
Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP3646).
创建时间：
2025-04-17
