European Mouse Mutant Archive

The European Mouse Mutant Archive – EMMA is the INFRAFRONTIER’s non-profit repository for the collection, archiving (via cryopreservation) and distribution of relevant mutant mouse and rat strains essential for basic biomedical research. The laboratory mouse is the most important mammalian model for studying genetic and multi-factorial diseases in human beings. The comprehensive physical and data resources of EMMA support basic biomedical and preclinical research, and the available research tools and mouse/rat models of human disease offer the opportunity to develop a better understanding of molecular disease mechanisms and may provide the foundation for the development of diagnostic, prognostic and therapeutic strategies.

欧洲小鼠突变资源库（European Mouse Mutant Archive，简称EMMA）是INFRAFRONTIER旗下的非营利性资源库，专注于收集、通过冷冻保存技术归档以及分发基础生物医学研究必需的相关突变型小鼠与大鼠品系。实验小鼠是研究人类遗传性疾病与多因素疾病的最重要哺乳动物模型。EMMA所拥有的完备实体资源与数据资源，可为基础生物医学及临床前研究提供支撑；其提供的各类研究工具以及人类疾病小鼠、大鼠模型，有助于研究者更深入地解析疾病的分子致病机制，并可为诊断、预后评估与治疗策略的开发奠定坚实基础。

搜集汇总

背景与挑战

背景概述

欧洲小鼠突变体档案（EMMA）是一个非营利性存储库，致力于收集、冷冻保存和分发对基础生物医学研究至关重要的突变小鼠和大鼠品系。作为欧洲主要的小鼠存储库和全球第三大非营利存储库，EMMA拥有超过9500个突变小鼠品系，其资源支持疾病机制研究和诊疗策略开发。