Processed data and results of the INFIMA paper

This Zenodo repository makes the processed data and the results of our INFIMA paper available. Our paper presents a method called INFIMA for <strong>In</strong>tegrative <strong>Fi</strong>ne-<strong>Ma</strong>pping with Model Organism Multi-Omics Data. INFIMA capitalizes on multi-omics data modalities such as chromatin accessibility and transcriptome from the eight Diversity Outbred (DO) mice founder strains to fine-map DO islet eQTL. In addition, INFIMA employs footprinting and <em>in silico</em> mutation analysis to reveal regulatory genetic variants that mediate strain-specific expression differences. The source code for reproducing the data can be found at Github. Please also check our Shiny app for data visualization!