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WP2197 - Endothelin pathways - Homo sapiens

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https://www.ndexbio.org/viewer/networks/162caa8d-5c69-11ec-b3be-0ac135e8bacf
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Endothelin-1 is a bicyclic 21 amino acid peptide, produced primarily in the endothelium. It is a potent stimulus of long-lasting and persistent vasoconstriction. It also has a role as a stimulus of inflammation, oxidative stress and cellular proliferation. Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP2197)
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2025-04-17
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