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Homo sapiens Raw sequence reads. Homo sapiens

NIAID Data Ecosystem2026-03-10 收录

CRISPRi基因编辑

癌症靶向治疗

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA397837 数据链接链接失效反馈

官方服务：

资源简介：

Cas9 and sgRNA-directed selective and efficient disruption of mutant KRAS in cancer cells

应用场景：

创建时间：

2017-08-10

癌细胞重编程

癌症靶向治疗

Depletion of Nrf2 leads to an increase in cellular ROS, reduced glutathione and thiols, and profound reprogramming of metabolism. Unbiased transcriptome analyses show that key enzymes of glycolysis, p

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File S2.zip

CRISPRi基因编辑

基因敲入序列分析

Annotated sequence files in .ape format (comparable with Genbank) of knock-ins generated by CRISPR/Cas9-mediated genome editing. Unmodified genomic sequence is also provided.

Figshare2023-03-14 更新20

Mus musculus 129S1/SvImJ CasX sites

CRISPRi基因编辑

小鼠基因组靶点预测

This is an annotated list of potential CasX (Cas12e) editing sites based on Ensembl Release 95 for Mus musculus 129S1/SvImJ. The sites are annotated with location contig, start, end, target sequence,

Figshare2019-03-18 更新20

Highly active sgRNAs for E. coli

CRISPRi基因编辑

细菌合成生物学

The best sgRNA for each gene, RBS and promoter in E. coli

Figshare2020-03-27 更新40

Development of Aptamer-DNAzyme Based Metal-Nucleic Acid Frameworks for Gastric Cancer therapy

核酸适配体药物递送

癌症靶向治疗

All data from source data

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