Type I interferon protects against bone loss in periodontitis by mitigating an interleukin (IL)-17-neutrophil axis [RNA-Seq]

We assessed the transcriptomic profile at the late stage on day 10 at the end of the ligature-induced periodontitis model through RNA-seq. We used the ligated gingival samples from the Ifnar1-/- mice and WT mice. The gingival tissues approximating the ligature were collected and RNA-seq were performed at the end of ligature model on day 10 post-ligature placement.