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Comparison of marker expression in abnormal tissue compared to normal epithelium.

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(a) Expression of E-cadherin, EMP1, 5T4 and N-cadherin in FEP, LGD, HGD, T1 OSCC and T4 OSCC biopsies compared to normal tissue (NT). (b) Expression of E-cadherin, EMP1, 5T4 and N-cadherin in FEP, LGD, HGD, T1 OSCC and T4 OSCC biopsies compared to an assumed linear relationship of FEP>LGD>HGD>T1 OSCC>T4 OSCC. (c) Hypothesis testing of an assumed linear NT>LGD>HGD relationship and putative linear HGD>T1 OSCC>T4 OSCC transition. Grey boxes show statistically significant results.

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2017-12-08
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